Hoppers had the lead with five minutes left, but a last minute try from Tynedale meant they took a draw back to the North East.
Tynedale scored the first try nearly 20 minutes in, when an excellent run from Euan Forlow saw him play in Seamus Hutton who had plenty of space to score.
There was a quick response from Hoppers though, Harry Holden grabbed his eighth try this season when the driving maul went over.
Dec Norrington was shown a yellow card for a high tackle, but Hoppers took the lead for the first time when Greg Smith scored his first penalty.
That was short lived however when Ben Bell scored after several attempts at the pick and drive from the visitors.
Hoppers closed out the first half with a penalty to keep the gap to three points heading into the break.
It only took three minutes for the hosts to score in the second half, again from a driving maul, but it was Alfie Longstaff who scored the try on his home debut for the side.
Tynedale bit back, when a long looping pass out wide landed in the hands of Will Roberts who tumbled over.
Smith added another three, but it was Tynedale who were on the front foot again, this time Joe Beaty scoring after an excellent nudge from Leslie saw the ball end up in his hands.
It was an excellent response from Hoppers, they won the ball from the restart, and a few quick passes saw Jake Maher score
There was a tense ending though, Smith scored a penalty to give Hoppers a seven point lead, but it was Tynedale had a chance to level Ben Haigh crashed over.
All eyes were on Leslie to level the game with a last minute conversion, who slotted it away to confirm a draw in an end to end affair.
Preston Grasshoppers head coach Dan Orwin was frustrated with the final outcome.
“We should’ve closed that one out,” said Orwin.
“I said to the players we’re very close to being a very good team but we’re not quite there yet.
“With a minute to go, we should be staying tight, keeping the ball, but we gave away the ball in our 22, and it was inevitable they were going to score.
“Feels like a missed opportunity again from our side.”
Match report by Tom Kelly